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Pure red cell hypoplasia associated with long-arm deletion of chromosome 5 |
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| Authors: | Joseph DiBenedetto Jr Teresita Padre-Mendoza Maurice M Albala |
| Institution: | (1) Division of Clinical Hematology, Rhode Island Hospital, Brown University Program in Medicine, 593 Eddy Street, 02902 Providence, Rhode Island, USA;(2) Genetics Section of Pathology, Rhode Island Hospital, Brown University Program in Medicine, 593 Eddy Street, 02902 Providence, Rhode Island, USA;(3) Present address: Roswell Park Memorial Institute, 14263 Buffalo, New York, USA |
| Abstract: | Summary A further instance of the new hematologic entity of pure red cell hypoplasia with deletion of the long arm of a chromosome 5(5q-) was seen in a 59-year-old white male. Examination of the bone marrow showed depressed erythroid cells with normal granulocytic and megakaryocytic precursors. Chromosomal analysis showed deletion of a chromosome 5 without any apparent translocation. This karyotype may be associated with acute leukemia. |
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