Glycosidation of alkylamino-alkan-1-ol. A simple and convenient synthesis of glycosylated cationic lipids |
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Authors: | Jacopin Christophe Egron Marie-José Scherman Daniel Herscovici Jean |
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Affiliation: | Laboratoire de Chimie Bioorganique et de Biotechnologie Moléculaire et Cellulaire. UMR 7001 CNRS-ENSCP-Aventis-Gencell. 11, rue Pierre et Marie Curie, 75231 Cedex, Paris, France. |
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Abstract: | Starting from long chain alkylamino-alkan-1-ol a series of amino glycolipids were synthesized. This procedure allows a short and convenient preparation of glycosylated cationic lipids for gene delivery. |
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