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Glycosidation of alkylamino-alkan-1-ol. A simple and convenient synthesis of glycosylated cationic lipids
Authors:Jacopin Christophe  Egron Marie-José  Scherman Daniel  Herscovici Jean
Affiliation:Laboratoire de Chimie Bioorganique et de Biotechnologie Moléculaire et Cellulaire. UMR 7001 CNRS-ENSCP-Aventis-Gencell. 11, rue Pierre et Marie Curie, 75231 Cedex, Paris, France.
Abstract:Starting from long chain alkylamino-alkan-1-ol a series of amino glycolipids were synthesized. This procedure allows a short and convenient preparation of glycosylated cationic lipids for gene delivery.
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