关于复制中医动物模型的思考

指出复制中医动物模型需要遵守4个基本的原则，即以中医理论为指导；复制的模型症状符合中医临床；相应的药物能够反证治疗；模型稳定，能重复。同时，认为复制理想的中医动物模型可以采取以下几个步骤，即：选择研究的病、证模型；了解相应病、证临床表现、病因、病理和病机；紧密关注临床，找寻适当造模因素；选择恰当造模动物；评判指标的选择；药物反证；重复验证。

Pondering on Copying Animal Model of Traditional Chinese Medicine

The author thought that copying animal model of traditional Chinese medicine (TCM) needed to observe following basic principles. Firstly, that was done under the guidance of the theory of TCM. Secondly, the duplicated symptoms of animal model should conform to those of clinic of TCM.Thirdly,the symptoms could be healed by corresponding medicine. Finally, the model must be stable and could be duplicated repeatedly. At the same time, duplicating an ideal animal model of TCM. several steps be followed. First of all, you should confirm what the researched animal model of sickness or syndrome is. Then, understand corresponding sickness or syndrome with clinical manifestation, cause of disease, pathology and pathogenesis, and pay close attention to clinic, look for the suitable factor and animal which would be used to copy model. Finally, appropriate judgement indications should be chosen, and medicine treatment, repetition confirmation should be considered too.