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Calcium and bioluminescent probes
Authors:Nicolas M T  Leclerc C  Moreau M
Affiliation:INSERM U432, Université Montpellier 2, place Eugène Bataillon, CC 089, F-34095 Montpellier.
Abstract:Ca2+ is an universal second messenger in numerous cell physiological processes. Aequorin, a bioluminescent calcium-binding protein is used today as a cellular probe to measure and image variations in calcium concentrations. The paper describes the characteristics and the use of aequorin as a luminescent calcium probe, and the future in the use of this protein for calcium imaging.
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