Evidence from comparative genomics for a complete sexual cycle in the 'asexual' pathogenic yeast <Emphasis Type="Italic">Candida glabrata</Emphasis>期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

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Evidence from comparative genomics for a complete sexual cycle in the 'asexual' pathogenic yeast <Emphasis Type="Italic">Candida glabrata</Emphasis>

Authors:	Simon?Wong Mario?A?Fares Wolfgang?Zimmermann Geraldine?Butler Email author" target="_blank">Kenneth?H?Wolfe Email author

Institution:	(1) Department of Genetics, Smurfit Institute, University of Dublin, Trinity College, Dublin 2, Ireland;(2) AGOWA, Glienicker Weg 185, D-12489 Berlin, Germany;(3) Department of Biochemistry and Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin 4, Ireland;

Abstract:	Background Candida glabrata is a pathogenic yeast of increasing medical concern. It has been regarded as asexual since it was first described in 1917, yet phylogenetic analyses have revealed that it is more closely related to sexual yeasts than other Candida species. We show here that the C. glabrata genome contains many genes apparently involved in sexual reproduction.

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