Presence of pancreatic-type phospholipase A2 mRNA in rat gastric mucosa and lung |
| |
| Authors: | T Sakata E Nakamura Y Tsuruta M Tamaki H Teraoka H Tojo T Ono M Okamoto |
| |
| Affiliation: | Shionogi Research Laboratories, Shionogi & Co., Ltd., Osaka, Japan. |
| |
| Abstract: | The content of mRNA for a pancreatic-type phospholipase A2 present in rat gastric mucosa was much greater than that in pancreas. In lung the mRNA for this pancreatic-type phospholipase A2 was also detected, but less than in pancreas. Nucleotide sequence analysis showed that these pancreatic-type phospholipase A2 cDNAs derived from rat gastric mucosa and lung were completely identical to that from rat pancreas (Ohara et al. (1986) J. Biochem. 99, 733-739). This demonstrates that the pancreatic-type phospholipase A2 present in gastric mucosa and lung does not originate from pancreas. |
| |
| Keywords: | |
|
|
