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In vitro beneficial activation of microglial cells by mechanically-injured astrocytes enhances the synthesis and secretion of BDNF through p38MAPK
Authors:Yang Hao  Feng Guo-Dong  Liang Zhe  Vitale Angela  Jiao Xi-Ying  Ju Gong  You Si-Wei
Institution:Institute of Neurosciences, The Fourth Military Medical University, Xi'an 710032, China. yanghao71_99@yahoo.com
Abstract:
Keywords:CNS  central nervous system  BDNF  brain-derived neurotrophic factor  ACM  astrocyte conditioned medium  NAS  normal astrocyte supernatant  MAPK  mitogen-activated protein kinase  FCS  fetal calf serum  DMEM  Dulbecco modified Eagle’s Medium  PLL  poly-L-lysine  EDTA  ethylenediamine tetraacetic acid  BCA  Bicinchoninic acid  ROS  Reactive oxygen species  ERK  extracellular signal regulated kinase  JNK  c-Jun N-terminal kinase  EGF  epidermal growth factor  IGF-1  insulin-like growth factor-1  TNF  tumor necrosis factor
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