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The prereplication complex recruits XEco2 to chromatin to promote cohesin acetylation in Xenopus egg extracts
Authors:Higashi Torahiko L  Ikeda Megumi  Tanaka Hiroshi  Nakagawa Takuro  Bando Masashige  Shirahige Katsuhiko  Kubota Yumiko  Takisawa Haruhiko  Masukata Hisao  Takahashi Tatsuro S
Institution:Graduate School of Frontier Biosciences, Osaka University, 1-3 Yamadaoka, Suita, Osaka 565-0871, Japan.
Abstract:
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  • Highlights? XEco2 loading and cohesin acetylation require pre-RC assembly but not DNA synthesis ? Two N-terminal motifs in XEco2 are essential for XEco2 loading and cohesion ? The PIP box in XEco2 contributes to cohesion ? Interaction of acetylated cohesin with DNA is stabilized after DNA replication
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