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New pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-ones as potent and selective PDE5 inhibitors |
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| Authors: | Feixas Joan Giovannoni Maria Paola Vergelli Claudia Gavaldà Amadeu Cesari Nicoletta Graziano Alessia Dal Piaz Vittorio |
| Institution: | Almirall Prodesfarma Research Center, Cardener 68-74, 08024 Barcelona, Spain. |
| Abstract: | A series of potent PDE5 inhibitors with high selectivity versus PDE6 isoenzymes was identified. |
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| 本文献已被 ScienceDirect PubMed 等数据库收录！ | |