The hypoxia-inducible factor is stabilized in circulating hematopoietic stem cells under normoxic conditions |
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| Authors: | Piccoli Claudia D'Aprile Annamaria Ripoli Maria Scrima Rosella Boffoli Domenico Tabilio Antonio Capitanio Nazzareno |
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| Affiliation: | Department of Biomedical Science, University of Foggia, Foggia, Italy. |
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| Abstract: | |
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| Keywords: | BM, bone marrow CsA, cyclosporin A DCF, dichlorofluorescein DFX, desferrioxamine DPI, diphenylene iodonium EA, human endothelial hybrid cell line (Ea.hy 926) EPO, erythropoietin G-CSF, granulocyte colony stimulating factor HIF, hypoxia-inducible factor HRE, hypoxia responsive element HSC, hematopoietic stem cell LMN, lymphomononuclear smallcaps" >l-NNMA, smallcaps" >l-monomethyl- smallcaps" >l-arginine LSCM, laser scanning confocal microscopy NOX, NADPH oxidase PB, peripheral blood PHD, prolyl hydroxylase pVHL, von Hippel-Lindau protein RNS, reactive nitrogen species ROS, reactive oxygen species |
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