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The hypoxia-inducible factor is stabilized in circulating hematopoietic stem cells under normoxic conditions |
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| Authors: | Piccoli Claudia D'Aprile Annamaria Ripoli Maria Scrima Rosella Boffoli Domenico Tabilio Antonio Capitanio Nazzareno |
| Institution: | Department of Biomedical Science, University of Foggia, Foggia, Italy. |
| Abstract: | |
| Keywords: | BM bone marrow CsA cyclosporin A DCF dichlorofluorescein DFX desferrioxamine DPI diphenylene iodonium EA human endothelial hybrid cell line (Ea hy 926) EPO erythropoietin G-CSF granulocyte colony stimulating factor HIF hypoxia-inducible factor HRE hypoxia responsive element HSC hematopoietic stem cell LMN lymphomononuclear l-NNMA" target="_blank">l-NNMA l-monomethyl-l-arginine" target="_blank">l-monomethyl-l-arginine LSCM laser scanning confocal microscopy NOX NADPH oxidase PB peripheral blood PHD prolyl hydroxylase pVHL von Hippel-Lindau protein RNS reactive nitrogen species ROS reactive oxygen species |
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