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A Sialylated Voltage-Dependent Ca2+ Channel Binds Hemagglutinin and Mediates Influenza A Virus Entry into Mammalian Cells
Authors:Yoichiro Fujioka  Shinya Nishide  Toyoyuki Ose  Tadaki Suzuki  Izumi Kato  Hideo Fukuhara  Mari Fujioka  Kosui Horiuchi  Aya O. Satoh  Prabha Nepal  Sayaka Kashiwagi  Jing Wang  Mika Horiguchi  Yuko Sato  Sarad Paudel  Asuka Nanbo  Tadaaki Miyazaki  Hideki Hasegawa  Yusuke Ohba
Affiliation:1. Department of Cell Physiology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo 060-8638, Japan;2. Laboratory of Biomolecular Science, Faculty of Pharmaceutical Science, Hokkaido University, Sapporo 060-0812, Japan;3. Department of Pathology, National Institute of Infectious Diseases, Tokyo 162-0052, Japan;4. Center for Research and Education on Drug Discovery, Faculty of Pharmaceutical Science, Hokkaido University, Sapporo 060-0812, Japan;5. Department of Probiotics Immunology, Institute for Genetic Medicine, Hokkaido University, Sapporo 060-0815, Japan;6. Whitman Center, Marine Biological Laboratory, Woods Hole, MA 02543, USA
Abstract:
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  • Keywords:influenza A virus  virus entry  calcium ion  calcium channel  calcium channel blockers  hemagglutinin  sialylation  virus-host cell interaction
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