An HhaI polymorphism is present in factor IX genes of Asian subjects |
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| Authors: | Alexander P. Reiner Arthur R. Thompson |
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| Affiliation: | (1) Puget Sound Blood Center, 98104 Seattle, WA, USA;(2) The University of Washington, 98104 Seattle, WA, USA;(3) Puget Sound Blood Center, 921 Terry Avenue, 98104 Seattle, WA, USA |
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| Abstract: | Summary Hemophilia B is caused by decreased factor IX procoagulant activity. An HhaI restriction site polymorphism near the factor IX gene has been detected by the polymerase chain reaction. Frequency and linkage data already observed in Caucasians are confirmed and the polymorphism is also prevalent in the factor IX genes of Black and Asian populations. |
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