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Synthesis and activity of selective MMP inhibitors with an aryl backbone |
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| Authors: | Barta T E Becker D P Bedell L J De Crescenzo G A McDonald J J Munie G E Rao S Shieh H S Stegeman R Stevens A M Villamil C I |
| Affiliation: | a Pharmacia, Department of Medicinal Chemistry, 4901 Searle Parkway, Skokie, IL 60077, USA b Pharmacia, Department of Medicinal Chemistry, 700 North Chesterfield Parkway, St. Louis, MO 63198, USA c Molecular Simulations, Inc., 736 Bellerive Manor Dr., St. Louis, MO 63141, USA |
| Abstract: | A series of novel, MMP-1 sparing arylhydroxamate sulfonamides with activity against MMP-2 and -13 is described. |
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