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P-component of amyloid: amino-terminal sequence
Authors:M Skinner  A S Cohen
Affiliation:1. Arthritis and Connective Tissue Disease Section of the Evans Department of Clinical Research, University Hospital, the Medical Service of the Boston City Hospital, Boston, Massachusetts 02118 USA;2. Department of Medicine, Boston University School of Medicine, Boston, Massachusetts 02118 USA
Abstract:A homogeneous preparation of P-component has been isolated from human splenic amyloid. Twenty-three residues of the amino-terminal sequence of this unique protein have been determined. The sequence is not that of an immunoglobulin and does not correspond to the sequence of any previously reported protein.
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