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Taste sensitivity may be used to predict pharmacological effects
Authors:C R Joyce  L Pan  D D Varonos
Affiliation:1. Urban Forest Research Group, Centre for Sustainable Forestry and Climate Change, Forest Research, Alice Holt Lodge, Farnham, GU10 4LH, UK;2. Department of Yield and Silviculture, Slovenian Forestry Institute, Večna pot 2, SI-1000, Ljubljana, Slovenia;1. UCD Institute of Food and Health, University College Dublin, Belfield, 4 Dublin, Ireland;2. Sensory Evaluation Center, The Pennsylvania State University, University Park, PA 16802, United States;3. Department of Food Science, The Pennsylvania State University, University Park, PA 16802, United States;4. Department of Food Science, The University of Massachusetts, Amherst, MA, 01002, United States;1. Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA 98195, USA;2. Department of Biological, Geological and Environmental Sciences (BiGeA), Laboratory of Molecular Anthropology and Centre for Genome Biology, University of Bologna, Via Selmi 3, 40126 Bologna, Italy;3. Department of Biology, University of Pisa, Via Ghini 13, 56126 Pisa, Italy;4. University of Gastronomic Sciences, Piazza Vittorio Emanuele 9, Bra, Pollenzo 12042, CN, Italy;5. Department of Experimental, Diagnostic and Specialty Medicine (DIMES), University of Bologna, Via San Giacomo 12, 40126 Bologna, Italy;1. Universidade Estadual do Centro-Oeste – UNICENTRO, Departamento de Química, Campus CEDETEG, Guarapuava, PR, Brazil;2. Catalan Institute of Nanoscience and Nanotechnology (ICN2), Campus UAB, Bellaterra 08193, Barcelona, Spain;3. Barcelona Institute of Science and Technology (BIST), Campus UAB, Bellaterra 08193, Barcelona, Spain;1. Dipartimento di Chimica, Biologia e Biotecnologie, via Elce di Sotto 8, I-06123 Perugia, Italy;2. Computational Laboratory for Hybrid/Organic Photovoltaics (CLHYO), CNR - ISTM, via Elce di Sotto 8, I-06123 Perugia, Italy;3. CompuNet, Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genova, Italy;1. Department of Environmental Health Sciences, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy;2. Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy;3. Department of Statistics and Quantitative Methods, Università Degli Studi di Milano-Bicocca, Milan, Italy;4. Department of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden;5. Department of Clinical Sciences and Community Health, Università Degli Studi di Milano, Milan, Italy;6. Department of Molecular and Translational Medicine, Università degli Studi di Brescia, Brescia, Italy;7. Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
Abstract:The hypothesis that taste and other kinds of receptor-mechanism have properties that can be quantitatively related has now been directly supported in two small samples (n = 22 and n = 16) of healthy, British medical students, for one drug and three measures of autonomic activity. The relationship was still strongly apparent after more than one year.
Keywords:
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