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Glucosyloxy alkaloids from Pancratium biflorum
Authors:Shibnath Ghosal  Yatendra Kumar  Shripati Singh
Institution:Pharmaceutical Chemistry Research Laboratory Department of Pharmaceutics, Banaras Hindu University, Varanasi-5, India
Abstract:From fluids of flower stems and bulbs, and from extracts of roots of Pancratium biflorum, collected at different stages of growth, three new glucosyloxy alkaloids, viz. hordenine-4-O-β-d-glucoside, lycorine-1-O-β-d-glucoside and pseudolycorine-1-O-β-d-glucoside, have been isolated and characterized. Additionally, three proto alkaloids, β-phenethylamine, tyramine and hordenine, together with four true alkaloids, lycorine, pseudolycorine, pretazettine and tazettine, encountered before in other memebrs of the Amaryllidaceae, have now been isolated also from this species. Ontogenic variations of alkaloidal constituents have been observed. The ability of the alkaloidal constituents to complex with divalent metal ions and phytosterols has been examined with a view to evaluating their significance in plant biochemistry.
Keywords:Amaryllidaceae  proto alkaloids  β-phenethylamine  tyramine  hordenine  alkaloids  lycorine  pseudolycorine  pretazettine  tazettine  glucosyloxy alkaloids  ontogenic variation  alkaloid-metal ion complex  alkaloid-sterol complex  root growth promoter  
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