Capsugenin,a dammarane triterpene from Corchorus capsularis |
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| Authors: | Choudhury M Hasan Aminul Islam Mahtabuddin Ahmed Mofizud-Din Ahmed Peter G Waterman |
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| Institution: | 1. Department of Pharmacy, University of Dhaka, Dhaka-2, Bangladesh Pakistan;2. Bangladesh Jute Research Institute (Technology Division), Dhaka-7 Pakistan;3. Department of Chemistry, University of Dhaka, Dhaka-2; Pakistan;4. Phytochemistry Research Laboratories, Department of Pharmacy (Pharmaceutical Chemistry), University of Strathclyde, Glasgow G1 1XW, U.K. |
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| Abstract: | From the leaves of Corchorus capsularis a new dammarane triterpene glycoside, capsin, has been isolated. Capsin was identified as the 3-glucoside of 20,24-epoxy-3β,12β,25,30-tetrahydroxydammarane from spectral data. Capsin was tentatively assigned the (20S, 24S)-configuration by comparison with data available for similar compounds. One of the oxidation products of the aglycone appears to be a friedo-type derivative, formed by concerted methyl migration on decarboxylation of a C-30 carboxylic acid intermediate. |
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| Keywords: | Tiliaceae dammarane triterpene capsin capsugenin |
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