Pfaffosides,nortriterpenoid saponins,from Pfaffia paniculata |
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| Authors: | Shiro Nakai Noriko Takagi Hiroaki Miichi Shinichi Hayashi Nobushige Nishimoto Tsunematsu Takemoto Haruhisa Kizu |
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| Institution: | 1. Research and Development Division, Rohto Pharmaceutical Co., Ltd., Tatsumi Nishi, Ikuno-ku, Osaka, 544, Japan;2. Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima, 770, Japan;3. School of Pharmacy, Hokuriku University, Kanagawa-machi, Kanazawa, 920-11, Japan |
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| Abstract: | Three new nortriterpene saponins having inhibitory effects on the growth of cultured tumor cells, named pfaffosides D, E and F, have been isolated from Pfaffia paniculata. Their structures have been established as 3β-O-β-d-xylopyranosyl-(1 → 2)-β-d-(6-O-n-butyl) glucuronopyranosyl]-pfaffic acid-(28 → 1)-β-d-glucopyranosyl ester, 3β-O-β-d-xylopyranosyl-(1 → 2)-β-d(6-O-methyl)glucuronopyranosyl]-pfaffic acid-(28 → 1)-β-d glucopyranosyl ester and 3β-Oβ-d-glucuronopyranosyl]-pfaffic acid respectively, based on their chemical and spectroscopic properties |
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| Keywords: | Amaranthaceae Brazil ginseng nortriterpenoid saponin pfaffosides |
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