Molluscicidal saponins from Gundelia tournefortii |
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Authors: | Hildebert Wagner Hubertus Nickl Y Aynehchi |
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Institution: | 1. College of Pharmacy, University of Teheran, Iran |
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Abstract: | From the roots of Gundelia tournefortii seven saponins have been isolated mainly by DCCC. The main saponins (A and B) were characterized, mainly by 13C and 1H NMR spectroscopy, as oleanolic acid 3-O-(2-α-l-arabinopyranosyl(1 → 3) -β-d-gentiotriosyl(1 → 6) -β-d-glucopyranosyl]gb-d-xylopyranoside) (saponin A) and oleanolic acid 3-O-(2-α-l-arabinopyranosyl] (1 → 3)-β-d-gentiobiosyl (1 → 6)-β-d-glucopyranosyl β-d-xylopyranoside) (saponin B). The other saponins are also derived from oleanolic acid and contain more sugar units. The saponin mixture and the saponins A and B possess strong molluscicidal activity against the schistosomiasis transmitting snail Biomphalaria glabrata. |
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Keywords: | Asteraceae triterpenoid saponins molluscicidal activity |
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