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Activation of NRF2 Signaling in HEK293 Cells by a First‐in‐Class Direct KEAP1‐NRF2 Inhibitor
Authors:Xia Wen  Gabriell Thorne  Longqin Hu  Melanie S. Joy  Lauren M. Aleksunes
Affiliation:1. Department of Pharmacology and Toxicology, Rutgers, The State University of New Jersey, Ernest Mario School of Pharmacy, Piscataway, NJ, USA;2. Department of Pharmacy and Health Professions, Elizabeth City State University, Elizabeth City, NC, USA;3. Medicinal Chemistry, Rutgers, The State University of New Jersey, Ernest Mario School of Pharmacy, Piscataway, NJ, USA;4. Department of Pharmaceutical Sciences, University of Colorado, Aurora, CO, USA;5. Environmental and Occupational Health Sciences Institute, Rutgers, The State University of New Jersey, Piscataway, NJ, USA
Abstract:
Keywords:NRF2  KEAP1  Nephrotoxicity  Kidney  HO‐1
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