Prevalence of anti-LAV antibodies in hemophiliacs, correlation with the immunological state |
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Authors: | J P Aymard C Janot J C Chermann M E Briquel P Perrier P Alexandre F Streiff |
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Abstract: | 49 french haemophiliacs (haemophilia A: 41 patients; haemophilia B: 8 patients) were serologicaly tested for LAV antibodies: 10 patients (20.4%) were seropositive including 9 (21.9%) with haemophilia A and 1 (12,5%) with haemophilia B. Between seronegative and seropositive patients total lymphocyte and T-lymphocyte sub-populations counts were not significantly different. The mean serum IgG level was higher and palpable lymphadenopathy more frequently encountered among seropositive patients. |
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