| Abstract: | As shown, formation of antibodies to the antigen-recognition receptors of T-lymphocytes was possible in a syngeneic system. The antiserum of CBA mice given intravenous injections of CBA lymphocytes, immune to C57BL cells, proved to specifically inhibit in a mixed culture blasttransformation of CBA T-lymphocytes only against the C57BL cells. The same antiserum failed to influence the proliferative activity of CBA T-lymphocytes reacting to the "foreign" antigen (DBA/2 cells). No antibodies against the C57BL cells were revealed in the antireceptor antiserum. It is assumed that the autoantireceptor antibodies had a regulatory effect on the immune response. |
