MSight: an image analysis software for liquid chromatography-mass spectrometry |
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| Authors: | Palagi Patricia M Walther Daniel Quadroni Manfredo Catherinet Sébastien Burgess Jennifer Zimmermann-Ivol Catherine G Sanchez Jean-Charles Binz Pierre-Alain Hochstrasser Denis F Appel Ron D |
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| Institution: | Proteome Informatics Group, Swiss Institute of Bioinformatics, Geneva, Switzerland. patricia.palagi@isb-sib.ch |
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| Abstract: | Images obtained from high-throughput mass spectrometry (MS) contain information that remains hidden when looking at a single spectrum at a time. Image processing of liquid chromatography-MS datasets can be extremely useful for quality control, experimental monitoring and knowledge extraction. The importance of imaging in differential analysis of proteomic experiments has already been established through two-dimensional gels and can now be foreseen with MS images. We present MSight, a new software designed to construct and manipulate MS images, as well as to facilitate their analysis and comparison. |
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