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Clavine alkaloid biosynthesis by the fungus <Emphasis Type="Italic">Penicillium palitans</Emphasis> Westling 1911 isolated from ancient permafrost deposits
Authors:A G Kozlovsky  V P Zhelifonova  T V Antipova
Institution:(1) Skryabin Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences, pr. Nauki 5, Pushchino, Moscow oblast, 142290, Russia
Abstract:The relic strain of Penicillium palitans isolated from the ancient permafrost deposits produces clavine alkaloids such as festuclavine, fumigaclavine A, and fumigaclavine B. Alkaloid biosynthesis is concurrent with the growth. Tryptophan and zinc ion additives to the culture medium stimulate the synthesis of alkaloids.
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