Advances in the analysis of DNA sequence variations using oligonucleotide microchip technology |
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Authors: | Tillib S V Mirzabekov A D |
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Affiliation: | Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 32 Vavilov Str., Moscow 117984, Russia. stillib@cityline.ru |
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Abstract: | The analysis of DNA variation (polymorphisms and mutations) on a genome-wide scale is becoming both increasingly important and technically challenging. An integration of a growing number of molecular biological methods of DNA-sequence analysis with the high-throughput feature of oligonucleotide microarray-based technologies is one of the most promising current directions of research and development. |
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