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A dead end for microRNAs
Authors:Ketting René F
Institution:Hubrecht Institute, Uppsalalaan 8, 3584 CT, Utrecht, Netherlands. ketting@niob.knaw.nl
Abstract:Dead end (Dnd1) is an RNA-binding protein that mediates germ-cell viability and suppresses the formation of germ-cell tumors. Kedde et al. (2007) now provide evidence that Dnd1 mediates these effects by counteracting microRNA-mediated silencing of mRNAs.
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