A dead end for microRNAs |
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Authors: | Ketting René F |
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Institution: | Hubrecht Institute, Uppsalalaan 8, 3584 CT, Utrecht, Netherlands. ketting@niob.knaw.nl |
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Abstract: | Dead end (Dnd1) is an RNA-binding protein that mediates germ-cell viability and suppresses the formation of germ-cell tumors. Kedde et al. (2007) now provide evidence that Dnd1 mediates these effects by counteracting microRNA-mediated silencing of mRNAs. |
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