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金黄色葡萄球菌及其L型感染对小鼠不育与致癌的研究
引用本文:汪万英,张世馥,姚敏,夏佩莹.金黄色葡萄球菌及其L型感染对小鼠不育与致癌的研究[J].中国微生态学杂志,1994(3).
作者姓名:汪万英  张世馥  姚敏  夏佩莹
作者单位:蚌埠医学院病理学教研室,蚌埠医学院微生物学教研室
摘    要:本文用金黄色葡萄球菌及其稳定的L型,经静脉和阴道注射等方式感染小鼠,发现金葡萄菌及其L型可引起小鼠不育并有致肿瘤的可能。用金葡菌及L型感染组小鼠的妊娠率仅为25~50%,对照组妊娠率为100%,P<0.01;同时发现感染组小鼠有6.3%发生恶性肿瘤,而且L型菌还可通过胎盘屏障引起子鼠的垂直感染。

关 键 词:金葡菌L型,妊娠率,垂直,感染,肿瘤

STUDY OF STAPHYIOCOCCUS AUREUS AND L-FORMS INFECTIONON STERILITY AND TUMOR-FORMATION OF MICE
Wang Wanying,et al..STUDY OF STAPHYIOCOCCUS AUREUS AND L-FORMS INFECTIONON STERILITY AND TUMOR-FORMATION OF MICE[J].Chinese Journal of Microecology,1994(3).
Authors:Wang Wanying  
Abstract:Sterility and tuinor formation were observed in mice aftersntravenaus and intravagina infection of staphyloccus aureus and stableL-forms.It was found that the rate of pregnancy in the infected groupwere 25-50% lower than the uninfected control group(P<0.01),6.3% of theinfected group were also shown to have tumor formation.In addition,thestaphylococcus L-forms may pass troughthe placental barrier and transmitvertically to the fetal mice.
Keywords:Staphylococcus L-forms Rate of pregnancy verticaltransm it iofi Tumor
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