Rec-mediated recombinational hot spot activity in bacteriophage lambda. III. Chi mutations are site-mutations stimulating rec-mediated recombination. |
| |
Authors: | F W Stahl J M Crasemann M M Stahl |
| |
Affiliation: | Institute of Molecular Biology University of Oregon Eugene, Ore. 97403, U.S.A. |
| |
Abstract: | Lambda phage defective for Red and gam function make small plaques on rec+ bacteria. Mutants (called Chi) of λ arise which suppress the small-plaque phenotype. Chi mutations arise at at least four well-separated sites; one site is between gene L and att, one is between att and gam, one is in the cII gene, and one is near gene S. A phage strain carrying a Chi mutation at a given site has an extraordinarily high rate of Rec-mediated crossing-over near that site. |
| |
Keywords: | |
本文献已被 ScienceDirect 等数据库收录! |