Murine sex-limited protein expression requires androgens and pituitary hormones |
| |
| Authors: | Theodore M Danoff Margaret B Goldman Dr John N Goldman |
| |
| Institution: | (1) Pritzker School of Medicine, University of Chicago, Chicago, Illinois, USA;(2) Department of Medicine, Michael Reese Hospital and Medical Center, Chicago, Illinois, USA;(3) Division of Infectious Diseases, The Milton S. Hershey Medical Center, The Pennsylvania State University, P. O. Box 850, 17033 Hershey, Pennsylvania, USA |
| |
| Abstract: | Levels of the murine sex-limited protein, (Slp) were measured by an enzyme-linked immunosorbent assay in normal and hypophysectomized female CDF1 (Slp
a) mice before and after a 15-day treatment with testosterone proprionate. Both groups of mice initially had undetectable levels of circulating Slp. After treatment, Slp serum levels of the nonhypophysectomized group had risen significantly above the Slp serum levels of the hypophysectomized group and the pretreatment controls. This indicates that the pituitary gland is necessary for the androgen-induced expression of Slp. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
