New developments in microarray technology |
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Authors: | Blohm D H Guiseppi-Elie A |
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Affiliation: | University of Bremen, FB2-UFT, Biotechnology and Molecular Genetics, D-28359 Bremen, Germany. dhb@biotec.uni-bremen.de |
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Abstract: | Microarrays have emerged as indispensable research tools for gene expression profiling and mutation analysis. New classification of cancer subtypes, dissecting the yeast metabolism and large-scale genotyping of human single nucleotide polymorphisms are important results being obtained with this technique. Realizing the microsphere-based massively parallel signature sequencing technique as fluid microarrays, building new types of protein arrays and constructing miniaturized flow-through systems, which can potentially take this technology from the research bench into industrial, clinical and other routine applications, exemplify the intense developments that are now ongoing in this field. |
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