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A stopped-flow laser turbidimeter for studying changes in the shape of cells stimulated by external agents
Authors:David A. Deranleau  Christoph Rothen  Marcus Streit  Daniel Dubler  Ernst F. Lüscher
Affiliation:University of Berne, Theodor Kocher Institute, Bern, Switzerland
Abstract:A laser turbidimeter suitable for following rapid morphological changes which may accompany the stimulation of cells suspended in an adequate medium is described. Stopped-flow mixing is used to initiate the reaction and the changes in light transmission are followed with a fast recording technique. The apparatus has been used to examine the ADP-induced shape change reaction of human blood platelets.
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