| 利用单克隆抗体鉴定人甲胎蛋白(HAFP)抗原结构可分性 |
| |
| 引用本文： | 虞伟,麦荫乔.利用单克隆抗体鉴定人甲胎蛋白(HAFP)抗原结构可分性[J].中国生物化学与分子生物学报,1986,2(1):41-46. |
| |
| 作者姓名： | 虞伟 麦荫乔 |
| |
| 作者单位： | 白求恩医科大学生物化学教研室 长春
(虞伟)，白求恩医科大学生物化学教研室 长春(麦荫乔) |
| |
| 摘 要： | 本文利用两株针对HAFP分子不同抗原决定簇的单克隆抗体,鉴定HAFP酶解片断的抗原抗体反应性质,并同完整HAFP分子进行比较。结果表明,酶解片断上失去了一株单克隆抗体所对应的分子部份,完整保留着另一株单克隆抗体所识别的抗原决定簇,从而证实HAFP分子某些抗原结构之间具有可分割性。
|
| 关 键 词： | 人甲胎蛋白 酶解片断 单克隆抗体 |
| 收稿时间： | 1986-02-20 |
SEPARABILITY OF ANTIGENIC STRUCTURE OF HUMAN ALPHA-FETOPROTEIN IS PROVED BY MONOCLONAL ANTIBODIES |
| |
| Yu,Wei Mai,Yin-Chiu.SEPARABILITY OF ANTIGENIC STRUCTURE OF HUMAN ALPHA-FETOPROTEIN IS PROVED BY MONOCLONAL ANTIBODIES[J].Chinese Journal of Biochemistry and Molecular Biology,1986,2(1):41-46. |
| |
| Authors: | Yu Wei Mai Yin-Chiu |
| |
| Institution: | (Department of Biochemistry,Bethune Medical University,Changchun |
| |
| Abstract: | A fragment of HAFP is determined by two monoclonal antibodies to HAFP and its antigen-antibody reactivity is compered with complete HAFP molecules.The results show that the fragment has lost the antigenic determinant able to be recognized by one of the monoclonal antibodies,but retains the determinant reactive to the other monoclonal antibody,thus prove that there are some separable antigenic structures in the HAFP monlecules. |
| |
| Keywords: | Human alpha-fetoprotein enzyme-digest fragment monoclonal antibody |
| 本文献已被 CNKI 等数据库收录！ |
| 点击此处可从《中国生物化学与分子生物学报》浏览原始摘要信息 |
| 点击此处可从《中国生物化学与分子生物学报》下载免费的PDF全文 |
