Increased taurine excretion in hereditary hyperprolinemia of the mouse |
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Authors: | R L Blake R V Grillo E S Russell |
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Affiliation: | The Jackson Laboratory, Bar Harbor, Maine 04609, Germany |
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Abstract: | The concentration of taurine in fresh urine samples of hyperprolinemic PRO/Re mice taken daily for five days was about 18.0 μmoles per ml urine compared to 3.2 for CBA/J mice. The concentration of taurine in plasma of PRO/Re mice was not elevated compared to CBA/J or C57BL/6J mice. When CBA/J mice are treated with proline the concentration of taurine in the urine increased. |
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