Transmission ratio distortion of mouse t haplotypes is not a consequence of wild-type sperm degeneration |
| |
Authors: | Lee M Silver Patricia Olds-Clarke |
| |
Institution: | 1. Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724 USA;2. Department of Anatomy, Temple University School of Medicine, Philadelphia, Pennsylvania 19140 USA |
| |
Abstract: | A mouse t-complex-specific DNA probe was used to determine the ratio of t-carrying and (+)-carrying sperm in epididymal, vas deferens, and postejaculatory sperm cell populations from heterozygous () mice with transmission ratios of greater than 95%. No detectable degeneration of (+)-carrying sperm was observed. In this respect, mouse t haplotypes differ from Drosophila melanogaster SD chromosomes. High transmission of t haplotypes must be a consequence of differential transport and/or differential sperm function during the fertilization process itself. |
| |
Keywords: | |
本文献已被 ScienceDirect 等数据库收录! |
|