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The dynamic mechanism of 4E-BP1 recognition and phosphorylation by mTORC1
Authors:Raphael Böhm  Stefan Imseng  Roman P Jakob  Michael N Hall  Timm Maier  Sebastian Hiller
Institution:1. Biozentrum, University of Basel, 4056 Basel, Switzerland
Abstract:
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  • Keywords:mTOR signaling  target of rapamycin  intrinsically disordered protein  atypical kinase  multi?site binding  hierarchical phosphorylation  protein dynamics  translational control  NMR spectroscopy  kinetic modelling
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