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FANCM regulates repair pathway choice at stalled replication forks
Authors:Arvind Panday  Nicholas A Willis  Rajula Elango  Francesca Menghi  Erin E Duffey  Edison T Liu  Ralph Scully
Institution:1. Department of Medicine, Division of Hematology-Oncology and Cancer Research Institute, Beth Israel Deaconess Medical Center, and Harvard Medical School, Boston, MA 02215, USA;2. The Jackson Laboratory for Genomic Medicine, Farmington, CT 06030, USA
Abstract:
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  • Keywords:FANCM  BRCA1  Fanconi anemia  Bloom’s syndrome helicase  genomic instability  homologous recombination  replication restart  break-induced replication  tandem duplication  synthetic lethality
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