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Loss of LUC7L2 and U1 snRNP subunits shifts energy metabolism from glycolysis to OXPHOS |
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| Authors: | Alexis A Jourdain Bridget E Begg Eran Mick Hardik Shah Sarah E Calvo Owen S Skinner Rohit Sharma Steven M Blue Gene W Yeo Christopher B Burge Vamsi K Mootha |
| Institution: | 1. Department of Molecular Biology and Howard Hughes Medical Institute, Massachusetts General Hospital, Boston, MA 02114, USA;2. Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA;3. Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA;4. Department of Biology, MIT, Cambridge, MA 02139, USA;5. Department of Cellular and Molecular Medicine, Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA 92093, USA |
| Abstract: |  |
| Keywords: | spliceosome MDS Tarui disease phosphofructokinase myelodysplastic syndrome 7q- cancer ferroptosis |
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