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Anti-malarial humoral immunity: the long and short of it |
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| Authors: | Kai J. Rogers Rahul Vijay Noah S. Butler |
| Affiliation: | 1. Department of Microbiology and Immunology, University of Iowa, Iowa City, IA, USA;2. Interdisciplinary Graduate Program in Immunology, The University of Iowa, Iowa City, IA, USA |
| Abstract: | Humoral immunity is critical for limiting Plasmodium parasite infections and the severity of malaria. Naturally acquired immunity against malaria occurs inefficiently and protection is relatively short-lived. Here we review recent advances and explore emerging hypotheses regarding the molecular and cellular pathways that regulate Plasmodium parasite-specific B cell responses and durable anti-malarial humoral immunity. |
| Keywords: | Malaria Metabolism Plasmablast Memory B cell Plasma cell Antibody |
| 本文献已被 ScienceDirect 等数据库收录！ | |