首页 | 本学科首页   官方微博 | 高级检索  
   检索      


EXO5-DNA structure and BLM interactions direct DNA resection critical for ATR-dependent replication restart
Authors:Shashank Hambarde  Chi-Lin Tsai  Raj K Pandita  Albino Bacolla  Anirban Maitra  Vijay Charaka  Clayton R Hunt  Rakesh Kumar  Oliver Limbo  Remy Le Meur  Walter J Chazin  Susan E Tsutakawa  Paul Russell  Katharina Schlacher  Tej K Pandita  John A Tainer
Institution:1. Department of Radiation Oncology, The Houston Methodist Research Institute, Houston, TX 77030, USA;2. Department of Neurosurgery, The Houston Methodist Research Institute, Houston, TX 77030, USA;3. Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA;4. Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA;5. Sheikh Ahmed Center for Pancreatic Cancer Research, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA;6. School of Biotechnology, Shri Mata Vashino Devi University, Katra, Jammu and Kashmir, 182320, India;7. Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA;8. Departments of Biochemistry and Chemistry and Center for Structural Biology, Vanderbilt University, Nashville, TN 37240, USA;9. Molecular Biophysics and Integrated Bioimaging, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA;10. Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
Abstract:
><ol class=
  • Download : Download high-res image (222KB)
  • Download : Download full-size image
  • Keywords:exonuclease  replication stress  fork restart  interstrand crosslink repair  Bloom  genetic instability  Fanconi anemia  ATR phosphorylation  sister chromatid exchange  SCE  tumor proliferation
    本文献已被 ScienceDirect 等数据库收录!
    设为首页 | 免责声明 | 关于勤云 | 加入收藏

    Copyright©北京勤云科技发展有限公司  京ICP备09084417号