Unveiling pharmacological studies provide new insights on Mangifera longipes and Quercus gomeziana |
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| Authors: | Bishwajit Guha Mohammad Arman Mohammad Nazmul Islam Syed Mohammed Tareq Md Masudur Rahman Shahenur Alam Sakib Rahul Mutsuddy Abu Montakim Tareq Talha Bin Emran Ali M Alqahtani |
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| Institution: | 1. Department of Pharmacy, Southern University Bangladesh, 739/A Mehedibag Road, Chittagong 4000, Bangladesh;2. Department of Pharmacy, International Islamic University Chittagong, Chittagong 4318, Bangladesh;3. Department of Theoretical and Computational Chemistry, University of Dhaka, Dhaka 1000, Bangladesh;4. Department of Pharmacy, BGC Trust University Bangladesh, Chittagong 4381, Bangladesh;5. Department of Pharmacology, College of Pharmacy, King Khalid University, Abha 62529, Saudi Arabia |
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| Abstract: | Mangifera longipes and Quercus gomeziana both is an ethnomedicinally important Asian herb that has been known for numerous healing activity of tribal people. The present research aims to investigate the phytochemical analysis with in vitro, in vivo possibilities of the soluble ethanol extract of M. longipes root (EEMLR) and Q. gomeziana leaves (EEQGL) by an experimental approach. The plant extract of EEMLR and EEQGL was found secondary metabolites, notably steroids, glycosides, tannins, flavonoids, saponins, gums, and alkaloids. Additionally, the extract showed significant activity in antioxidant, antipyretic, anti-inflammatory, membrane stabilization, cytotoxic, thrombolytic, and analgesic activities while no response in antibacterial activity. Our findings reveal that soluble ethanol extract of EEMLR and EEQGL is safe, which can be an effective source for exploring new medicinal products. This research's outcomes may provide potentials for mitigating pyrexia, inflammation, pain, cellular toxicity, and coagulation. |
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| Keywords: | Antipyretic Anti-inflammatory Analgesic Antioxidant EEMLR"} {"#name":"keyword" "$":{"id":"k0040"} "$$":[{"#name":"text" "$$":[{"#name":"__text__" "_":"Ethanol extract of "} {"#name":"italic" "_":"Mangifera longipe"} {"#name":"__text__" "_":" leaves root EEQGL"} {"#name":"keyword" "$":{"id":"k0050"} "$$":[{"#name":"text" "$$":[{"#name":"__text__" "_":"Ethanol extract of "} {"#name":"italic" "_":"Quercus gomeziana"} {"#name":"__text__" "_":" leaves ASA"} {"#name":"keyword" "$":{"id":"k0060"} "$$":[{"#name":"text" "_":"Acetyl salicylic acid Half maximal inhibitory concentration Lethal Concentration 50 DPPH"} {"#name":"keyword" "$":{"id":"k0090"} "$$":[{"#name":"text" "_":"2 2-diphenyl-1-picrylhydrazyl TLC"} {"#name":"keyword" "$":{"id":"k0100"} "$$":[{"#name":"text" "_":"Thin-layer chromatography |
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