Virulence regulator AphB enhances toxR transcription in Vibrio cholerae |
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| Authors: | Xiao Xu Andrew M Stern Zhi Liu Biao Kan Jun Zhu |
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| Affiliation: | (1) State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, Beijing, PR China;(2) Department of Microbiology, University of Pennsylvania School of Medicine, 19104 Philadelphia, PA, USA |
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| Abstract: | Background Vibrio cholerae is the causative agent of cholera. Extensive studies reveal that complicated regulatory cascades regulate expression of virulence genes, the products of which are required for V. cholerae to colonize and cause disease. In this study, we investigated the expression of the key virulence regulator ToxR under different conditions. |
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