HL-A genotype of patients with acute lymphoblastic leukaemia |
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| Authors: | D. P. Singal N. Naipaul R. Berry M. K. Pai A. Zipursky |
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| Affiliation: | (1) Department of Surgery, McMaster University, Hamilton, Ontario;(2) Department of Paediatrics, McMaster University, Hamilton, Ontario |
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| Abstract: | Summary 10 patients with acute lymphoblastic leukaemia were tissue-typed for 21 HL-A specificities. Of these, genotypes of 9 pateints were determined by family analyses. Haplotype HL-A1,8 occurred in 5 out of 18 instances. On phenotype basis, a slight increase was observed in the incidence of antigens HL-A1 and HL-A8. No loss of HL-A specificities could be detected on lymphocytes through family analyses. |
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