Resection guided by antibodies (REGAJ) a reappraisal after 10 years |
| |
Authors: | Jäger W Ackermann S |
| |
Institution: | Department of Obstetrics and Gynecology, University of Erlangen-Nuremberg-Germany. |
| |
Abstract: | Between 1986 and 1990 50 patients with ovarian cancer were submitted to a procedure which we called REGAJ-resection guided by antibodies. Using the radiolabelled murine monoclonal antibody OC 125, microscopic ovarian tumors producing CA 125 were detected during second-look surgery by a hand-held probe. Retrospective analysis after 10 years revealed that this procedure resulted in the cure of 4 of 11 patients, who would otherwise have been considered tumor free during second-look surgery and not further treated. Previous problems associated with the method can now be solved so that the clinical value of the procedure should be reconsidered. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|