Enhancement of Enzyme-Catalyzed Production of Reactive Oxygen Species by Suspensions of “Crocidolite” Asbestos Fibres |
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| Authors: | Erich F Elstner Wolfgang Schutz Georg Vogl J V Bannister |
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| Institution: |
a Institute of Botany and Mikrobiology Technical University of Munich, Munich, Germany |
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| Abstract: | Ethylene release from methylthio-ketobutyric acid is an indicator for activated oxygen species of the OH '-radical type. Xanthine oxidase plus xanthine or diaphorase in the presence of NADH and j uglone produce OH'-type oxy-radicals. The production of reactive oxygen species in these enzymatic systems is enhanced by “crocidolite” asbestos fibres. |
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| Keywords: | Asbestos oxygen activation xanthine oxidase NADH-diaphorase lung diseases |
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