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C. elegans aging: proteolysis cuts both ways
Authors:Bowerman Bruce
Affiliation:Institute of Molecular Biology, University of Oregon, Eugene, OR 97403, USA. bbowerman@molbio.uoregon.edu
Abstract:Recent reports from two laboratories working on the nematode Caenorhabditis elegans have identified both positive and negative roles for ubiquitin-mediated proteolysis in the regulation of longevity by the insulin/insulin-like growth factor signaling pathway.
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