C. elegans aging: proteolysis cuts both ways |
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Authors: | Bowerman Bruce |
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Affiliation: | Institute of Molecular Biology, University of Oregon, Eugene, OR 97403, USA. bbowerman@molbio.uoregon.edu |
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Abstract: | Recent reports from two laboratories working on the nematode Caenorhabditis elegans have identified both positive and negative roles for ubiquitin-mediated proteolysis in the regulation of longevity by the insulin/insulin-like growth factor signaling pathway. |
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