| 硬孔灵芝的化学成分研究 |
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| 引用本文： | 赵芬李晔,刘超李保明,陈若芸. 硬孔灵芝的化学成分研究[J]. 菌物学报, 2009, 28(3): 407-409 |
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| 作者姓名： | 赵芬李晔 刘超李保明 陈若芸 |
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| 作者单位： | 中国医学科学院北京协和医学院药物研究所,中草药物质基础与资源利用教育部重点实验室,北京,100050;福建仙芝楼生物科技有限公司,福州,350002 |
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| 基金项目： | 科技部基础性工作专项基金 |
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| 摘 要： | 采用硅胶柱层析法进行分离纯化,从硬孔灵芝Ganoderma duropora的氯仿萃取物中分离得到甾类化合物8种。根据波谱数据,化合物1-8结构分别被鉴定为:麦角甾醇、麦角甾-7,22-二烯-3β-醇、麦角甾-7,22-二烯-3-酮、6,9-环氧麦角甾-7,22-二烯-3β-醇、过氧麦角甾醇、3,5-二羟基麦角甾-7,22-二烯-6-酮、β-谷甾醇和胡萝卜苷。
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| 关 键 词： | 硅胶柱层析 甾类化合物 灵芝 |
Chemical components from the fruiting bodies of Ganoderma duropora |
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| ZHAO Fen LI Ye LIU Chao LI Bao-Ming CHEN Ruo-Yun. Chemical components from the fruiting bodies of Ganoderma duropora[J]. Mycosystema, 2009, 28(3): 407-409 |
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| Authors: | ZHAO Fen LI Ye LIU Chao LI Bao-Ming CHEN Ruo-Yun |
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| Affiliation: | Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Beijing 100050, China |
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| Abstract: | Compounds were isolated from Ganoderma duropora fruit-body by silica gel column chromatography. Eight sterols were obtained from CHCl3 fraction of EtOH extract. Eight sterols were identified as ergosterol; ergosta-7, 22-dien-3β-ol; ergosta-7, 22-dien-3-one; 6, 9-epidioxyergosta-7, 22-dien-3β-ol; 5, 8-epidioxiergosta-6, 22-dien-3β-ol; 3, 5-dihydroxy-ergosta- 7, 22-dien-6-one; β-sitosterol; daucosterol by analyses of their Electro spray ionization-mass spectrometry, Electro ionization-mass spectrometry and Neonatal mortality rate data. |
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| Keywords: | silica gel column chromatography sterols Ganoderma |
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