Crystallization and preliminary crystallographic investigation of a DNA-RNA hybrid |
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| Authors: | S R Holbrook I Tinoco T S Young S H Kim F H Martin |
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| Affiliation: | 1. Department of Chemistry and Laboratory of Chemical Biodynamics University of California Berkeley, Calif. 94720, U.S.A.;2. Department of Chemistry University of Colorado Boulder, Col. 80309. U.S.A. |
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| Abstract: | A complex between the complementary hexanucleotides ribo-C-A-A-A-A-G and deoxyribo-C-T-T-T-T-G has been crystallized. The space group was determined to be P21 with unit cell dimensions . The crystals contain both the ribo- and the deoxyribo-hexanucleotide strands in a ratio of approximately 1:1. Each asymmetric unit contains the equivalent of four hybrid molecules. |
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