Antibiotic Resistance Genes Online (ARGO): a Database on vancomycin and beta-lactam resistance genes |
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Authors: | Scaria Joy Chandramouli Umamaheswaran Verma Sanjay Kumar |
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Institution: | Center for Biotechnology, Biological Sciences Group, Birla Institute of Technology & Science, Pilani-333031, India. |
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Abstract: | Vancomycin and beta-lactams are antibiotics that inhibit gram positive bacteria by interfering with cell wall synthesis. However, continuous use of antibiotics results in the emergence of multi-drug resistant (MDR) bacterial strains. Here, we describe ARGO, a database containing gene sequences conferring resistance to these two classes of antibiotics. It is designed as a resource to enhance research on the prevalence and spread of antibiotic resistance genes. ARGO is the first attempt to compile the resistance gene sequence data with state specific information. AVAILABILITY: AGRO is available for free at http://www.argodb.org/ |
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