Chromenes from Peperomia serpens (Sw.) Loudon (Piperaceae) |
| |
Authors: | Saga Kitamura Rodrigo O Romoff Paulete Young Maria Cláudia M Kato Massuo J Lago João Henrique G |
| |
Affiliation: | Faculdade de Ciências Biológicas, Exatas e Experimentais, Universidade Presbiteriana Mackenzie, 01302-970 S?o Paulo - SP, Brazil. |
| |
Abstract: | Chromatographic separation of the CH2Cl2 extract from leaves of Peperomia serpens yielded two chromenes [5-hydroxy-8-(3',7'-dimethylocta-2',6'-dienyl)-2,2,7-trimethyl-2H-1-chromene (1) and 5-hydroxy-8-(3'-methyl-2'-butenyl)-2,2,7-trimethyl-2H-1-chromene-6-carboxylic acid (2)], besides the known chromene [methyl 5-hydroxy-2,2,7-trimethyl-2H-1-chromene-6-carboxylate (3)] and the flavonoid, dihydrooroxylin (4). Their structural elucidation were achieved by spectroscopic analyses. The antifungal activities of the CH2Cl2 extract and the isolated chromenes were measured bioautographically against Cladosporium cladosporioides and C. sphaerospermum, when it was found that the crude extract showed higher activity as compared to the pure compounds. |
| |
Keywords: | Peperomia serpens Piperaceae Chromenes |
本文献已被 ScienceDirect PubMed 等数据库收录! |
|